Fine LG, Barnett EV, Danovitch GM, et al. SLE occurs frequently in women at reproductive age, and is associated with pregnancy complications. Pregnancy remains a commonly encountered but high-risk situation in this setting. Petri M. Systemic lupus erythematosus and pregnancy. ABSTRACT: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease most commonly involving skin, joints, and kidneys. Both maternal and fetal mortality and morbidity are still significantly increased despite improvements in outcomes. Rheum Dis Clin North America 20:87117, 1994. Systemic lupus erythematosus (SLE) is an autoimmune disease with a strong female predilection. Pregnancy is no longer considered an impossibility if you have lupus. Advancing technology and better understanding of the disease and its effects on the body have improved pregnancy outcomes over … Flares typically occur during the first or second trimester and are often mild. Ann Intern Med 94:667-677, 1981. Materna … However, pregnancy with the most common – and serious – type of the disease of lupus called systemic lupus erythematosus involves special implications for prenatal care. Having lupus doesn’t mean you can’t have a baby. As SLE is associated with higher risk of adverse pregnancy outcomes, such as preeclampsia and intrauterine growth restriction, compared with the general population, the patient underwent supplementary fetal surveillance with Doppler sonography in the third trimester at monthly intervals. 6 In patients with SLE, pregnancy loss occurs mostly during the first trimester. Systemic lupus erythematosus in pregnancy Patrick Gordon, Trevor Beedham, Munther Khamashta, David D’Cruz When a woman is known to have systemic lupus erythematosis, planning and preparation can improve the outcome of pregnancy and reduce the severity of … Active SLE at the time of conception is a strong predictor of adverse maternal and obstetrical outcomes [ 1-3 ]. Posted On: February 16, 2017 By Nathan D. Fox, MD. Systemic lupus erythematosus in pregnancy. PREGNANCY PLANNING — Ideally, disease should be quiescent for six months prior to systemic lupus erythematosus (SLE) patients attempting conception. And while pregnant women with active lupus may have symptoms, only 10 percent of those with SLE experience severe episodes during pregnancy. The key to a successful pregnancy is knowing how lupus affects the body and keeping the disease under control. Lupus and Pregnancy. This monograph provides an overview of the role of an obstetrician–gynecologist (ob-gyn) in the treatment of SLE … Pregnancy, though, is considered high-risk due to a combination of maternal (lupus flare, diabetes, pre-eclampsia) and fetal (miscarriage, intrauterine fetal demise, preterm birth, intrauterine growth restriction, congenital heart block) risks. Systemic Lupus Erythematosus (SLE) and Pregnancy. 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